The Difference Between Naltrexone and Vivitrol

The Difference Between Naltrexone and Vivitrol

When it comes to managing alcohol dependence or opioid use disorder, medications like naltrexone and Vivitrol often come up as potential treatment options. While they share some similarities, their differences are crucial in determining the best fit for an individual’s needs. This post dives into the distinctions between naltrexone and Vivitrol, helping you make informed decisions about your treatment journey.

What Is Naltrexone?

Naltrexone is a medication approved by the FDA to treat alcohol and opioid use disorders. It works by blocking opioid receptors in the brain, which reduces cravings and the rewarding effects of alcohol or opioids (O’Malley & Froehlich, 2003). Naltrexone is available in two main forms:

1. Oral Tablet: Taken daily, this form of naltrexone requires consistent adherence to a dosing schedule, which can be a challenge for some individuals.
2. Injectable (Extended-Release): Marketed under the brand name Vivitrol, this version is administered once a month by a healthcare provider.

What Is Vivitrol?

Vivitrol is the extended-release injectable form of naltrexone. It delivers a steady dose of the medication over 30 days, offering convenience and eliminating the need for daily pills. Like oral naltrexone, Vivitrol blocks opioid receptors, reducing cravings and the potential for relapse (Comer et al., 2006).

Key Differences Between Naltrexone and Vivitrol

1. Formulation and Administration

• Naltrexone: Available as a daily oral tablet, which requires self-administration.
• Vivitrol: Administered as a monthly injection by a healthcare provider, providing extended coverage.

2. Dosing Convenience

• Naltrexone: Daily dosing may be suitable for individuals who can maintain a routine but poses challenges for those prone to forgetting or skipping doses.
• Vivitrol: The monthly injection ensures consistent medication levels and eliminates the need for daily dosing.

3. Cost and Insurance Coverage

• Naltrexone: Generic oral tablets are generally more affordable and widely covered by insurance plans.
• Vivitrol: The injectable form is significantly more expensive, though many insurance providers offer coverage. Copay assistance programs may also be available.

4. Suitability and Monitoring

• Naltrexone: Oral naltrexone may be a better option for individuals with a fear of needles or those who prefer more control over their treatment schedule.
• Vivitrol: Ideal for individuals who struggle with medication adherence or prefer a “set it and forget it” approach.

5. Side Effects

Both naltrexone and Vivitrol share common side effects, including nausea, headache, fatigue, and injection site reactions (specific to Vivitrol). However, the extended-release nature of Vivitrol may minimize fluctuations in medication levels, potentially reducing certain side effects associated with oral naltrexone.

Which Option Is Right for You?

The choice between oral naltrexone and Vivitrol depends on several factors, including your lifestyle, treatment goals, and healthcare provider’s recommendations. Here are a few considerations:

• Adherence: If you find it challenging to stick to a daily medication routine, Vivitrol’s monthly injection may be a better fit.
• Cost: If affordability is a concern, generic oral naltrexone could be the more accessible option.
• Medical History: Discuss your health history and preferences with your healthcare provider to determine which option aligns best with your needs.

Final Thoughts

Both naltrexone and Vivitrol are powerful tools in the fight against alcohol and opioid use disorders. Understanding their differences helps ensure you choose a treatment that supports your recovery journey (Kranzler & Soyka, 2018). Consult with your healthcare provider to explore these options and find the solution that works best for you.

If you have questions about naltrexone or Vivitrol or want to learn more about how these treatments can fit into your recovery plan, reach out to our team. We’re here to guide you every step of the way!

At Choose Your Horizon, we’re dedicated to helping individuals on their recovery journey. If you’re exploring naltrexone, complete our online assessment and discover our tailored treatment plans to support your needs.