What Medicine Can Help to Quit Drinking?

Quitting or reducing alcohol consumption is a challenge for many, but medication-assisted treatment (MAT) has made it easier for individuals to regain control over their drinking habits. If you’re wondering what medicines can help you quit drinking, this guide will explore the most effective options, how they work, and how to determine the right one for you.

FDA-Approved Medications to Help Quit Drinking

The following medications have been approved by the Food and Drug Administration (FDA) to treat alcohol use disorder (AUD):

1. Naltrexone (Oral and Injectable - Vivitrol)

• How It Works: Naltrexone blocks the brain’s opioid receptors, reducing the pleasurable effects of alcohol and decreasing cravings.
• Who It’s Best For: Individuals who want to drink less or quit entirely.
• Dosage Forms: Available as a daily 50mg tablet or a monthly injection (Vivitrol).
• Research: Studies show that individuals using naltrexone experience fewer drinking days and lower relapse rates (Kranzler & Soyka, 2018).

2. Acamprosate (Campral)

• How It Works: Acamprosate helps stabilize brain chemistry after quitting alcohol, reducing post-acute withdrawal symptoms such as anxiety, insomnia, and mood swings.
• Who It’s Best For: Those who have already stopped drinking and want to maintain sobriety.
• Dosage Forms: Typically taken as two 333mg tablets three times a day.
• Effectiveness: Works best when combined with behavioral therapy and counseling.

3. Disulfiram (Antabuse)

• How It Works: Disulfiram creates an unpleasant reaction (nausea, vomiting, headache) when alcohol is consumed, acting as a deterrent.
• Who It’s Best For: People who are highly motivated to quit drinking and want an additional layer of accountability.
• Dosage Forms: Taken as a 250mg or 500mg tablet once daily.
• Considerations: Requires strict adherence, as drinking while on Disulfiram can cause severe side effects.

Off-Label Medications That May Help Quit Drinking

While not FDA-approved for alcohol use disorder, the following medications have shown promise in helping people reduce drinking:

4. Topiramate (Topamax)

• How It Works: Originally used for epilepsy and migraines, topiramate reduces alcohol cravings by altering brain neurotransmitters.
• Research: Some studies suggest it can help people drink less, but side effects like dizziness and memory issues may occur.

5. Baclofen

• How It Works: A muscle relaxant that may reduce alcohol cravings and withdrawal symptoms.
• Research: Studies show mixed results, but some individuals have found it helpful for managing alcohol dependence.

Which Medication Is Right for You?

Choosing the right medication depends on your drinking habits, health history, and personal goals. Some medications work better for reducing drinking, while others are ideal for maintaining long-term sobriety. A Choose Your Horizon healthcare provider can help determine the best option based on your needs.

A Better Way to Quit Drinking

Many people believe quitting alcohol requires an expensive rehab stay, but telehealth options now make treatment more accessible and affordable. With online assessments and virtual prescriptions, getting started with medication-assisted treatment has never been easier.

Take the First Step Today

If you're ready to explore medication options to help you drink less or quit drinking, we’re here to help. Complete our online assessment today to receive personalized recommendations and start your journey to a healthier future.